Anti-CGRP antibody [SRM14748] (STJ11109478)

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STJ11109478
£118.50 - £521.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : SRM14748
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity purification
Dilution Range: WB, 1:2000-1:8000
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CALCA
Gene ID: 796
Uniprot ID: CALCA_HUMAN
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Tissue Specificity Expressed in spinal cord.
Function CGRP1/CALCA is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex. Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. CGRP1 can also bind and activate CALCR-RAMP1 (AMYR1) receptor complex.
Protein Name Calcitonin Gene-Related Peptide 1
Cgrp1
Alpha-Type Cgrp
Calcitonin Gene-Related Peptide I
Cgrp-I
Database Links Reactome: R-HSA-418555
Reactome: R-HSA-419812
Reactome: R-HSA-977225
Cellular Localisation Secreted
Alternative Antibody Names Anti-Calcitonin Gene-Related Peptide 1 antibody
Anti-Cgrp1 antibody
Anti-Alpha-Type Cgrp antibody
Anti-Calcitonin Gene-Related Peptide I antibody
Anti-Cgrp-I antibody
Anti-CALCA antibody
Anti-CALC1 antibody

Information sourced from Uniprot.org

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