| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | CALCB |
| Gene ID: | 797 |
| Uniprot ID: | CALCB_HUMAN |
| Immunogen Region: | 20-120 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-120 of human CGPR. (NP_000719.1). |
| Immunogen Sequence: | AGSLQAAPFRSALESSPDPA TLSKEDARLLLAALVQDYVQ MKASELKQEQETQGSSSAAQ KRACNTATCVTHRLAGLLSR SGGMVKSNFVPTNVGSKAFG R |
| Tissue Specificity | Expressed in spinal cord, pituitary and thalamus. |
| Function | CALCB/CGRP2 is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex. Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. |
| Protein Name | Calcitonin Gene-Related Peptide 2Cgrp2Beta-Type CgrpBeta-CgrpCalcitonin Gene-Related Peptide IiCgrp-Ii |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-419812 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Calcitonin Gene-Related Peptide 2 antibodyAnti-Cgrp2 antibodyAnti-Beta-Type Cgrp antibodyAnti-Beta-Cgrp antibodyAnti-Calcitonin Gene-Related Peptide Ii antibodyAnti-Cgrp-Ii antibodyAnti-CALCB antibodyAnti-CALC2 antibody |
Information sourced from Uniprot.org