| Function | Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. |
| Protein Name | Complement Factor BC3/C5 ConvertaseGlycine-Rich Beta GlycoproteinGbgPbf2Properdin Factor B Cleaved Into - Complement Factor B Ba Fragment - Complement Factor B Bb Fragment |
| Database Links | Reactome: R-HSA-173736Reactome: R-HSA-174577Reactome: R-HSA-977606 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Complement Factor B antibodyAnti-C3/C5 Convertase antibodyAnti-Glycine-Rich Beta Glycoprotein antibodyAnti-Gbg antibodyAnti-Pbf2 antibodyAnti-Properdin Factor B Cleaved Into - Complement Factor B Ba Fragment - Complement Factor B Bb Fragment antibodyAnti-CFB antibodyAnti-BF antibodyAnti-BFD antibody |
Information sourced from Uniprot.org
