| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Ceramide kinase is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CERK |
| Gene ID: | 64781 |
| Uniprot ID: | CERK1_HUMAN |
| Specificity: | This antibody detects endogenous levels of CERK at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human CERK |
| Function | Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Shows a greater preference for D-erythro isomer of ceramides. Binds phosphoinositides. |
| Protein Name | Ceramide Kinase Hcerk Acylsphingosine Kinase Lipid Kinase 4 Lk4 |
| Database Links | Reactome: R-HSA-9840309 |
| Cellular Localisation | Cytoplasm Cell Membrane Peripheral Membrane Protein |
| Alternative Antibody Names | Anti-Ceramide Kinase antibody Anti-Hcerk antibody Anti-Acylsphingosine Kinase antibody Anti-Lipid Kinase 4 antibody Anti-Lk4 antibody Anti-CERK antibody Anti-KIAA1646 antibody |
Information sourced from Uniprot.org