Anti-CEP350 antibody (671-720 aa) (STJ92225)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CEP35 at the amino acid range 671-720
General Information
| Short Description | Rabbit polyclonal anti-Centrosome-associated protein 350 (671-720 aa) for use in IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CEP350 |
| Gene ID | 9857 |
| Uniprot ID | CE350_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CEP35 at the amino acid range 671-720 |
| Immunogen Region | 671-720 aa |
| Specificity | CEP350 Polyclonal Antibody detects endogenous levels of CEP350 protein. |
Additional Info
| Post Translational Modifications | Phosphorylated during mitosis. |
| Function | Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CPAP. Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network. Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity. Required for ciliation. |
| Protein Name | Centrosome-Associated Protein 350Cep350Centrosome-Associated Protein Of 350 Kda |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeSpindleNucleusCentrioleCilium Basal BodyAssociated With Mitotic SpindlesNuclearIn Discrete FociAssociated With Intermediate FilamentsAlso Present In The Pericentrosomal AreaLocalizes On Both Mother And Daughter CentriolesLocalizes To An Axial Position On The Mother CentrioleLocalizes To The Distal End Of The Centriole On The Subdistal Appendage Region |
| Alternative Antibody Names | Anti-Centrosome-Associated Protein 350 antibodyAnti-Cep350 antibodyAnti-Centrosome-Associated Protein Of 350 Kda antibodyAnti-CEP350 antibodyAnti-CAP350 antibodyAnti-KIAA0480 antibodyAnti-GM133 antibody |
Information sourced from Uniprot.org