| Host: | Rabbit |
| Applications: | IHC/IF/WB |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Centromere protein M (30-110 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC-P 1:50-200WB 1:500-2000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CENPM |
| Gene ID: | 79019 |
| Uniprot ID: | CENPM_HUMAN |
| Immunogen Region: | 30-110 aa |
| Specificity: | This antibody detects endogenous levels of human CENP-M |
| Immunogen: | Synthesized peptide derived from the human CENP-M at the amino acid range 30-110 |
| Function | Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. |
| Protein Name | Centromere Protein MCenp-MInterphase Centromere Complex Protein 39Proliferation-Associated Nuclear Element Protein 1 |
| Database Links | Reactome: R-HSA-141444Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-5663220Reactome: R-HSA-606279Reactome: R-HSA-68877Reactome: R-HSA-9648025 |
| Cellular Localisation | NucleusCytoplasmChromosomeCentromereKinetochoreNuclear In Non-Confluent Cells And Cytoplasmic In Confluent Or Dividing CellsLocalizes In The Kinetochore Domain Of Centromeres |
| Alternative Antibody Names | Anti-Centromere Protein M antibodyAnti-Cenp-M antibodyAnti-Interphase Centromere Complex Protein 39 antibodyAnti-Proliferation-Associated Nuclear Element Protein 1 antibodyAnti-CENPM antibodyAnti-C22orf18 antibodyAnti-ICEN39 antibodyAnti-PANE1 antibody |
Information sourced from Uniprot.org
