• Western blot analysis of various lysates using CELF6 Rabbit polyclonal antibody (STJ119788) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3min.

Anti-CELF6 antibody (230-380) (STJ119788)

SKU:
STJ119788

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CELF6 (230-380) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CELF6
Gene ID: 60677
Uniprot ID: CELF6_HUMAN
Immunogen Region: 230-380
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 230-380 of human CELF6 (NP_443072.3).
Immunogen Sequence: LGAFHPAPLPLGACGAYTTA ILQHQAALLAAAQGPGLGPV AAVAAQMQHVAAFSLVAAPL LPAAAANSPPGSGPGTLPGL PAPIGVNGFGPLTPQTNGQP GSDTLYNNGLSPYPAQSPGV ADPLQQAYAGMHHYAAAYPS AYAPVSTAFPQ
Tissue Specificity Expressed mainly in kidney, brain and testis and present in other tissues albeit at lower levels. Also expressed in fetal kidney.
Function RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA.
Protein Name Cugbp Elav-Like Family Member 6
Celf-6
Bruno-Like Protein 6
Cug-Bp- And Etr-3-Like Factor 6
Rna-Binding Protein Brunol-6
Cellular Localisation Nucleus
Cytoplasm
Alternative Antibody Names Anti-Cugbp Elav-Like Family Member 6 antibody
Anti-Celf-6 antibody
Anti-Bruno-Like Protein 6 antibody
Anti-Cug-Bp- And Etr-3-Like Factor 6 antibody
Anti-Rna-Binding Protein Brunol-6 antibody
Anti-CELF6 antibody
Anti-BRUNOL6 antibody

Information sourced from Uniprot.org

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