| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CELF6 |
| Gene ID: | 60677 |
| Uniprot ID: | CELF6_HUMAN |
| Immunogen Region: | 230-380 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 230-380 of human CELF6 (NP_443072.3). |
| Immunogen Sequence: | LGAFHPAPLPLGACGAYTTA ILQHQAALLAAAQGPGLGPV AAVAAQMQHVAAFSLVAAPL LPAAAANSPPGSGPGTLPGL PAPIGVNGFGPLTPQTNGQP GSDTLYNNGLSPYPAQSPGV ADPLQQAYAGMHHYAAAYPS AYAPVSTAFPQ |
| Tissue Specificity | Expressed mainly in kidney, brain and testis and present in other tissues albeit at lower levels. Also expressed in fetal kidney. |
| Function | RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA. |
| Protein Name | Cugbp Elav-Like Family Member 6Celf-6Bruno-Like Protein 6Cug-Bp- And Etr-3-Like Factor 6Rna-Binding Protein Brunol-6 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Cugbp Elav-Like Family Member 6 antibodyAnti-Celf-6 antibodyAnti-Bruno-Like Protein 6 antibodyAnti-Cug-Bp- And Etr-3-Like Factor 6 antibodyAnti-Rna-Binding Protein Brunol-6 antibodyAnti-CELF6 antibodyAnti-BRUNOL6 antibody |
Information sourced from Uniprot.org