| Short Description : | Rabbit polyclonal CELF5 (1-45) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CELF5 |
| Gene ID: | 60680 |
| Uniprot ID: | CELF5_HUMAN |
| Immunogen Region: | 1-45 |
| Immunogen Sequence: | MARLTESEARRQQQQLLQPR PSPVGSSGPEPPGGQPDGMK DLDAI |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-45 of human CELF5 (NP_001166144.1). |
| Tissue Specificity | Expressed in brain. |
| Function | RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA. |
| Protein Name | Cugbp Elav-Like Family Member 5Celf-5Bruno-Like Protein 5Cug-Bp- And Etr-3-Like Factor 5Rna-Binding Protein Brunol-5 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Cugbp Elav-Like Family Member 5 antibodyAnti-Celf-5 antibodyAnti-Bruno-Like Protein 5 antibodyAnti-Cug-Bp- And Etr-3-Like Factor 5 antibodyAnti-Rna-Binding Protein Brunol-5 antibodyAnti-CELF5 antibodyAnti-BRUNOL5 antibody |
Information sourced from Uniprot.org
