Anti-CEL antibody (350-550) (STJ114978)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CEL (350-550) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CEL |
| Gene ID | 1056 |
| Uniprot ID | CEL_HUMAN |
| Immunogen Region | 350-550 |
| Immunogen Sequence | IDMPAINKGNKKVTEEDFYK LVSEFTITKGLRGAKTTFDV YTESWAQDPSQENKKKTVVD FETDVLFLVPTEIALAQHRA NAKSAKTYAYLFSHPSRMPV YPKWVGADHADDIQYVFGKP FATPTGYRPQDRTVSKAMIA YWTNFAKTGDPNMGDSAVPT HWEPYTTENSGYLEITKKMG SSSMKRSLRTNFLRYWTLTY L |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 350-550 of human CEL (NP_001798.2). |
Additional Info
| Tissue Specificity | Mammary gland and pancreas. Detected in pancreatic and duodenal juice (at protein level). Expressed by eosinophils. |
| Post Translational Modifications | N- and O-glycosylated. |
| Function | Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs. Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins. |
| Protein Name | Bile Salt-Activated LipaseBal Bile Salt-Stimulated LipaseBsslBucelipaseCarboxyl Ester LipaseCholesterol EsterasePancreatic LysophospholipaseSterol Esterase |
| Database Links | Reactome: R-HSA-192456Reactome: R-HSA-9925561 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Bile Salt-Activated Lipase antibodyAnti-Bal antibodyAnti-Bile Salt-Stimulated Lipase antibodyAnti-Bssl antibodyAnti-Bucelipase antibodyAnti-Carboxyl Ester Lipase antibodyAnti-Cholesterol Esterase antibodyAnti-Pancreatic Lysophospholipase antibodyAnti-Sterol Esterase antibodyAnti-CEL antibodyAnti-BAL antibody |
Information sourced from Uniprot.org