• Immunofluorescence analysis of PANC-1 cells using CD66e monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
  • Anti-CEACAM5 antibody [3G12] (STJ97931)
  • Western blot analysis using CD66e monoclonal antibody against HEK293 (1) and CEA-hIgGFc transfected HEK293 (2) cell lysate.

Anti-CEACAM5 antibody [3G12] (STJ97931)

SKU:
STJ97931

£139.00 - £336.00
Current Stock:
Host: Mouse
Applications: WB/IF/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Carcinoembryonic antigen-related cell adhesion molecule 5 is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.
Clonality: Monoclonal
Clone ID: 3G12
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CEACAM5
Gene ID: 1048
Uniprot ID: CEAM5_HUMAN
Specificity: CD66e Monoclonal Antibody detects endogenous levels of CD66e protein.
Immunogen: Purified recombinant fragment of human CD66e expressed in E. Coli.
Post Translational Modifications Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
Function Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression.induces resistance to anoikis of colorectal carcinoma cells. (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer.
Protein Name Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5
Carcinoembryonic Antigen
Cea
Meconium Antigen 100
Cd Antigen Cd66e
Database Links Reactome: R-HSA-163125
Reactome: R-HSA-202733
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Apical Cell Membrane
Cell Surface
Localized To The Apical Glycocalyx Surface
Alternative Antibody Names Anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 antibody
Anti-Carcinoembryonic Antigen antibody
Anti-Cea antibody
Anti-Meconium Antigen 100 antibody
Anti-Cd Antigen Cd66e antibody
Anti-CEACAM5 antibody
Anti-CEA antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance