Anti-CDKN1C antibody (241-290 aa) (STJ96707)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human p57Kip2 around the non-acetylation site of Lys278 at the amino acid range 241-290
General Information
| Short Description | Rabbit polyclonal anti-Cyclin-dependent kinase inhibitor 1C (241-290 aa) for use in WB, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC-P 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDKN1C |
| Gene ID | 1028 |
| Uniprot ID | CDN1C_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human p57Kip2 around the non-acetylation site of Lys278 at the amino acid range 241-290 |
| Immunogen Region | 241-290 aa |
| Specificity | p57 Polyclonal Antibody detects endogenous levels of p57 protein. |
Additional Info
| Function | Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life. |
| Protein Name | Cyclin-Dependent Kinase Inhibitor 1cCyclin-Dependent Kinase Inhibitor P57P57kip2 |
| Database Links | Reactome: R-HSA-69231Reactome: R-HSA-9661069 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Cyclin-Dependent Kinase Inhibitor 1c antibodyAnti-Cyclin-Dependent Kinase Inhibitor P57 antibodyAnti-P57kip2 antibodyAnti-CDKN1C antibodyAnti-KIP2 antibody |
Information sourced from Uniprot.org