| Short Description : | Rabbit polyclonal anti-Threonylcarbamoyladenosine tRNA methylthiotransferaseA37 methylthiotransferase (10-59 aa) for use in WB and ELISA in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000ELISA 1:40000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CDKAL1 |
| Gene ID: | 54901 |
| Uniprot ID: | CDKAL_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human CDKAL at the amino acid range 10-59 |
| Immunogen Region: | 10-59 aa |
| Specificity: | CDKAL1 Polyclonal Antibody detects endogenous levels of CDKAL1 protein. |
| Function | Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine. |
| Protein Name | Threonylcarbamoyladenosine Trna MethylthiotransferaseCdk5 Regulatory Subunit-Associated Protein 1-Like 1Trna-T(6a37 Methylthiotransferase |
| Database Links | Reactome: R-HSA-6782315 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinIs A Tail-Anchored Protein That Exploits The Tcr40 Pathway For Insertion Into The Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Threonylcarbamoyladenosine Trna Methylthiotransferase antibodyAnti-Cdk5 Regulatory Subunit-Associated Protein 1-Like 1 antibodyAnti-Trna-T(6a37 Methylthiotransferase antibodyAnti-CDKAL1 antibody |
Information sourced from Uniprot.org
