| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CDK10 (1-283) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CDK10 |
| Gene ID: |
8558 |
| Uniprot ID: |
CDK10_HUMAN |
| Immunogen Region: |
1-283 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human CDK10 (NP_001092003.2). |
| Immunogen Sequence: |
MDKEKDGIPISSLREITLLL RLRHPNIVELKEVVVGNHLE SIFLVMGYCEQDLASLLENM PTPFSEAQVKCIVLQVLRGL QYLHRNFIIHRDLKVSNLLM TDKGCVKTADFGLARAYGVP VKPMTPKVVTLWYRAPELLL GTTTQTTSIDMWAVGCILAE LLAHRPLLPGTSEIHQIDLI VQLLGTPSENIWPGFSKLPL VGQYSLRKQPYNNLKHKFPW LSEAGLRLLHFLFMATAGD |
| Function | Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells). Involved in the regulation of actin cytoskeleton organization through the phosphorylation of actin dynamics regulators such as PKN2. Is a negative regulator of ciliogenesis through phosphorylation of PKN2 and promotion of RhoA signaling. |
| Protein Name | Cyclin-Dependent Kinase 10Cell Division Protein Kinase 10Serine/Threonine-Protein Kinase Pisslre |
| Cellular Localisation | CytoplasmCytoskeletonCilium Basal Body |
| Alternative Antibody Names | Anti-Cyclin-Dependent Kinase 10 antibodyAnti-Cell Division Protein Kinase 10 antibodyAnti-Serine/Threonine-Protein Kinase Pisslre antibodyAnti-CDK10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
