Anti-CDH11 antibody (421-470) (STJ94589)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human CDH11. AA range:421-470
General Information
| Short Description | Rabbit polyclonal anti-Cadherin-11 (421-470) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDH11 |
| Gene ID | 1009 |
| Uniprot ID | CAD11_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CDH11. AA range:421-470 |
| Immunogen Region | 421-470 |
| Specificity | OB-cadherin Polyclonal Antibody detects endogenous levels of OB-cadherin protein. |
Additional Info
| Tissue Specificity | Expressed mainly in brain but also found in other tissues. Expressed in neuroblasts. In the embryo from 67 to 72 days of gestation, detected at high levels in facial mesenchyme including the central palatal mesenchyme, dental mesenchyme, the eye and optic muscle, and the tongue (at protein level). |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. Required for proper focal adhesion assembly. Involved in the regulation of cell migration. |
| Protein Name | Cadherin-11Osf-4Osteoblast CadherinOb-Cadherin |
| Database Links | Reactome: R-HSA-418990Reactome: R-HSA-9759811Reactome: R-HSA-9762292Reactome: R-HSA-9833576 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cadherin-11 antibodyAnti-Osf-4 antibodyAnti-Osteoblast Cadherin antibodyAnti-Ob-Cadherin antibodyAnti-CDH11 antibody |
Information sourced from Uniprot.org