| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Cell division control protein 45 homolog (90-170 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CDC45 |
| Gene ID: | 8318 |
| Uniprot ID: | CDC45_HUMAN |
| Immunogen Region: | 90-170 aa |
| Specificity: | CDC45 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 90-170 |
| Function | Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. |
| Protein Name | Cell Division Control Protein 45 HomologPorc-Pi-1 |
| Database Links | Reactome: R-HSA-176187Reactome: R-HSA-176974Reactome: R-HSA-68962Reactome: R-HSA-69205 |
| Cellular Localisation | NucleusChromosomeAssociates With Chromatin |
| Alternative Antibody Names | Anti-Cell Division Control Protein 45 Homolog antibodyAnti-Porc-Pi-1 antibodyAnti-CDC45 antibodyAnti-CDC45L antibodyAnti-CDC45L2 antibodyAnti-UNQ374 antibodyAnti-PRO710 antibody |
Information sourced from Uniprot.org
