| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | CDC40 |
| Gene ID: | 51362 |
| Uniprot ID: | PRP17_HUMAN |
| Immunogen Region: | 1-100 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human CDC40 (NP_056975.1). |
| Immunogen Sequence: | MSAAIAALAASYGSGSGSES DSDSESSRCPLPAADSLMHL TKSPSSKPSLAVAVDSAPEV AVKEDLETGVHLDPAVKEVQ YNPTYETMFAPEFGPENPFR |
| Post Translational Modifications | Undergoes isomerization of the peptide bond between Gly-94 and Pro-95. The reaction is catalyzed by PPIL1. |
| Function | Required for pre-mRNA splicing as component of the activated spliceosome. Plays an important role in embryonic brain development.this function does not require proline isomerization. |
| Protein Name | Pre-Mrna-Processing Factor 17 Cell Division Cycle 40 Homolog Eh-Binding Protein 3 Ehb3 Prp17 Homolog Hprp17 |
| Database Links | Reactome: R-HSA-159236 Reactome: R-HSA-72163 Reactome: R-HSA-72187 Reactome: R-HSA-73856 |
| Cellular Localisation | Nucleus Nucleus Speckle |
| Alternative Antibody Names | Anti-Pre-Mrna-Processing Factor 17 antibody Anti-Cell Division Cycle 40 Homolog antibody Anti-Eh-Binding Protein 3 antibody Anti-Ehb3 antibody Anti-Prp17 Homolog antibody Anti-Hprp17 antibody Anti-CDC40 antibody Anti-EHB3 antibody Anti-PRP17 antibody Anti-PRPF17 antibody |
Information sourced from Uniprot.org