Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Monkey |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Cell division cycle protein 23 homolog (251-300 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000ELISA 1:20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CDC23 |
Gene ID: | 8697 |
Uniprot ID: | CDC23_HUMAN |
Immunogen Region: | 251-300 aa |
Specificity: | Cdc23 Polyclonal Antibody detects endogenous levels of Cdc23 protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human APC8 at the amino acid range 251-300 |
Function | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. |
Protein Name | Cell Division Cycle Protein 23 HomologAnaphase-Promoting Complex Subunit 8Apc8Cyclosome Subunit 8 |
Database Links | Reactome: R-HSA-141430Reactome: R-HSA-174048Reactome: R-HSA-174084Reactome: R-HSA-174154Reactome: R-HSA-174178Reactome: R-HSA-174184Reactome: R-HSA-176407Reactome: R-HSA-176408Reactome: R-HSA-176409Reactome: R-HSA-176412Reactome: R-HSA-179409Reactome: R-HSA-2467813Reactome: R-HSA-2559582Reactome: R-HSA-68867Reactome: R-HSA-69017Reactome: R-HSA-8853884Reactome: R-HSA-9687136Reactome: R-HSA-983168 |
Alternative Antibody Names | Anti-Cell Division Cycle Protein 23 Homolog antibodyAnti-Anaphase-Promoting Complex Subunit 8 antibodyAnti-Apc8 antibodyAnti-Cyclosome Subunit 8 antibodyAnti-CDC23 antibodyAnti-ANAPC8 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance