![Western blot analysis of lysates from wild type (WT) and CDA knockout (KO) HeLa cells, using [KO Validated] CDA Rabbit polyclonal antibody (STJ11100721) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/89659/358157/STJ11100721_1__02526.1713122458.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and CDA knockout (KO) HeLa cells, using [KO Validated] CDA Rabbit polyclonal antibody (STJ11100721) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.")
![Western blot analysis of lysates from wild type (WT) and CDA knockout (KO) HeLa cells, using [KO Validated] CDA Rabbit polyclonal antibody (STJ11100721) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/89659/358157/STJ11100721_1__02526.1713122458.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and CDA knockout (KO) HeLa cells, using [KO Validated] CDA Rabbit polyclonal antibody (STJ11100721) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.")
| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CDA |
| Gene ID: | 978 |
| Uniprot ID: | CDD_HUMAN |
| Immunogen Region: | 1-146 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-146 of human CDA (NP_001776.1). |
| Immunogen Sequence: | MAQKRPACTLKPECVQQLLV CSQEAKKSAYCPYSHFPVGA ALLTQEGRIFKGCNIENACY PLGICAERTAIQKAVSEGYK DFRAIAIASDMQDDFISPCG ACRQVMREFGTNWPVYMTKP DGTYIVMTVQELLPSSFGPE DLQKTQ |
| Tissue Specificity | Highly expressed in granulocytes while expression is very low in fibroblasts, chondrocytes, monocytes, and T- as well as B-cell lines. |
| Function | This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. |
| Protein Name | Cytidine DeaminaseCytidine Aminohydrolase |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-73614 |
| Alternative Antibody Names | Anti-Cytidine Deaminase antibodyAnti-Cytidine Aminohydrolase antibodyAnti-CDA antibodyAnti-CDD antibody |
Information sourced from Uniprot.org