Anti-CD87/PLAUR/uPAR antibody [8B12] (STJA0021592)

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STJA0021592
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: ELISA/SPR
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Urokinase Plasminogen Activator Surface Receptor is suitable for use in ELISA and SPR research applications.
Clonality : Monoclonal
Clone ID : 8B12
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: PLAUR
Gene ID: 5329
Uniprot ID: UPAR_HUMAN
Function Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Protein Name Urokinase Plasminogen Activator Surface Receptor
U-Par
Upar
Monocyte Activation Antigen Mo3
Cd Antigen Cd87
Database Links Reactome: R-HSA-162791
Reactome: R-HSA-6798695
Reactome: R-HSA-75205
Cellular Localisation Cell Membrane
Cell Projection
Invadopodium Membrane
Colocalized With Fap (Seprase) Preferentially At The Cell Surface Of Invadopodia Membrane In A Cytoskeleton-
Integrin- And Vitronectin-Dependent Manner
Isoform 1: Cell Membrane
Lipid-Anchor
Gpi-Anchor
Isoform 2: Secreted
Alternative Antibody Names Anti-Urokinase Plasminogen Activator Surface Receptor antibody
Anti-U-Par antibody
Anti-Upar antibody
Anti-Monocyte Activation Antigen Mo3 antibody
Anti-Cd Antigen Cd87 antibody
Anti-PLAUR antibody
Anti-MO3 antibody
Anti-UPAR antibody

Information sourced from Uniprot.org

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