| Tissue Specificity | Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain. |
| Function | Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. |
| Protein Name | Urokinase Plasminogen Activator Surface ReceptorU-ParUparMonocyte Activation Antigen Mo3Cd Antigen Cd87 |
| Database Links | Reactome: R-HSA-162791Reactome: R-HSA-6798695Reactome: R-HSA-75205 |
| Cellular Localisation | Cell MembraneCell ProjectionInvadopodium MembraneColocalized With Fap (Seprase) Preferentially At The Cell Surface Of Invadopodia Membrane In A Cytoskeleton-Integrin- And Vitronectin-Dependent MannerIsoform 1: Cell MembraneLipid-AnchorGpi-AnchorIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Urokinase Plasminogen Activator Surface Receptor antibodyAnti-U-Par antibodyAnti-Upar antibodyAnti-Monocyte Activation Antigen Mo3 antibodyAnti-Cd Antigen Cd87 antibodyAnti-PLAUR antibodyAnti-MO3 antibodyAnti-UPAR antibody |
Information sourced from Uniprot.org
