Anti-CD83 antibody [SAA2066] {FITC} (STJA0028534)

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STJA0028534
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: FC
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal anti-Cd83 antigen for use in FC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : SAA2066
Conjugation: FITC
Isotype: IgG1k
Formulation: PBS pH 7.4, 50% glycerol, 0.05% proclin300
Purification: Purified
Concentration: 0.5 mg/mL
Storage Instruction: Store at 4°C for 12 months. Protect from light. Do not freeze.
Gene Symbol: Cd83
Gene ID: 12522
Uniprot ID: CD83_MOUSE
Function Transmembrane glycoprotein predominantly found on the surface of many immune cells including dendritic cells or lymphocytes that plays various roles in immune response regulation. Plays an essential role in CD4(+) T-selection, differentiation and stability by regulating the activity of the major E3 ubiquitin ligase responsible for controlling MHC II trafficking MARCHF8. Also inhibits MARCHF1 association with MHC II and ubiquitination of MHCII. In addition, acts as an important modulator of protective responses against acute infections.
Protein Name Cd83 Antigen
Mcd83
Cd Antigen Cd83
Database Links
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Cd83 Antigen antibody
Anti-Mcd83 antibody
Anti-Cd Antigen Cd83 antibody
Anti-Cd83 antibody

Information sourced from Uniprot.org

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