Anti-CD70 antibody [FR70] {APC} (STJA0029388)

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STJA0029388
£282.50 - £423.50
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Host: Mouse
Applications: FC
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-Cd70 antigen is suitable for use in Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : FR70
Conjugation: APC
Isotype: IgG1
Formulation: 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Purification: Purified
Concentration: 0.5 mg/mL
Storage Instruction: Store at 4°C for 12 months. Protect from light. Do not freeze.
Gene Symbol: Cd70
Gene ID: 21948
Uniprot ID: CD70_MOUSE
Post Translational Modifications N-glycosylated.
Function Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells. The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells.
Protein Name Cd70 Antigen
Cd27 Ligand
Cd27-L
Tumor Necrosis Factor Ligand Superfamily Member 7
Cd Antigen Cd70
Database Links Reactome: R-MMU-5669034
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-Cd70 Antigen antibody
Anti-Cd27 Ligand antibody
Anti-Cd27-L antibody
Anti-Tumor Necrosis Factor Ligand Superfamily Member 7 antibody
Anti-Cd Antigen Cd70 antibody
Anti-Cd70 antibody
Anti-Cd27l antibody
Anti-Cd27lg antibody
Anti-Tnfsf7 antibody

Information sourced from Uniprot.org