| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S5109RM |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:5000-1:20000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CD7 |
| Gene ID: | 924 |
| Uniprot ID: | CD7_HUMAN |
| Immunogen Region: | 26-180 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-180 of human CD7. (NP_006128.1). |
| Immunogen Sequence: | AQEVQQSPHCTTVPVGASVN ITCSTSGGLRGIYLRQLGPQ PQDIIYYEDGVVPTTDRRFR GRIDFSGSQDNLTITMHRLQ LSDTGTYTCQAITEVNVYGS GTLVLVTEEQSQGWHRCSDA PPRASALPAPPTGSALPDPQ TASALPDPPAASALP |
| Tissue Specificity | Expressed on T-cells and natural killer (NK) cells and their precursors. |
| Function | Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1. In turn, mediates the production of cytokines such as IL-2. On resting NK-cells, CD7 activation results in a significant induction of interferon-gamma levels. |
| Protein Name | T-Cell Antigen Cd7Gp40T-Cell Leukemia AntigenT-Cell Surface Antigen Leu-9Tp41Cd Antigen Cd7 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-T-Cell Antigen Cd7 antibodyAnti-Gp40 antibodyAnti-T-Cell Leukemia Antigen antibodyAnti-T-Cell Surface Antigen Leu-9 antibodyAnti-Tp41 antibodyAnti-Cd Antigen Cd7 antibodyAnti-CD7 antibody |
Information sourced from Uniprot.org