| Host: | Mouse |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-T-cell antigen CD7 (1-100 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | ABT035 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2ak |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | IHC-P 1:100-500WB 1:200-1000IF 1:100-500 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CD7 |
| Gene ID: | 924 |
| Uniprot ID: | CD7_HUMAN |
| Immunogen Region: | 1-100 aa |
| Specificity: | The antibody can specifically recognize human CD7 protein.In western blotting of Jurkat cell lysate, there shows a 37KDa band detected by the antibody. |
| Immunogen: | Synthesized peptide derived from the human CD7 at the amino acid range 1-100 |
| Function | Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1. In turn, mediates the production of cytokines such as IL-2. On resting NK-cells, CD7 activation results in a significant induction of interferon-gamma levels. |
| Protein Name | T-Cell Antigen Cd7Gp40T-Cell Leukemia AntigenT-Cell Surface Antigen Leu-9Tp41Cd Antigen Cd7 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-T-Cell Antigen Cd7 antibodyAnti-Gp40 antibodyAnti-T-Cell Leukemia Antigen antibodyAnti-T-Cell Surface Antigen Leu-9 antibodyAnti-Tp41 antibodyAnti-Cd Antigen Cd7 antibodyAnti-CD7 antibody |
Information sourced from Uniprot.org