![Anti-CD66e/CEA/CEACAM5 nanobody [SAA1298] (STJN000113)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/200726/412908/STJN000113-SDS-PAGE-1__25348.1749232445.jpg?c=1 "Anti-CD66e/CEA/CEACAM5 nanobody [SAA1298] (STJN000113)")
![Anti-CD66e/CEA/CEACAM5 nanobody [SAA1298] (STJN000113)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/200726/412908/STJN000113-SDS-PAGE-1__25348.1749232445.jpg?c=1 "Anti-CD66e/CEA/CEACAM5 nanobody [SAA1298] (STJN000113)")
Anti-CD66e/CEA/CEACAM5 nanobody [SAA1298] (STJN000113)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-Cell Adhesion Molecule Ceacam5 is suitable for use in ELISA, Flow Cytometry and SPR research applications. |
| Applications | ELISA/FC/SPR |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1298 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | CEACAM5 |
| Gene ID | 1048 |
| Uniprot ID | CEAM5_HUMAN |
Additional Info
| Post Translational Modifications | Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate. |
| Function | Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression.induces resistance to anoikis of colorectal carcinoma cells. (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. |
| Protein Name | Cell Adhesion Molecule Ceacam5Carcinoembryonic AntigenCeaCarcinoembryonic Antigen-Related Cell Adhesion Molecule 5Cea Cell Adhesion Molecule 5Meconium Antigen 100Cd Antigen Cd66e |
| Database Links | Reactome: R-HSA-163125Reactome: R-HSA-202733 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorApical Cell MembraneCell SurfaceLocalized To The Apical Glycocalyx Surface |
| Alternative Nanobody Names | Anti-Cell Adhesion Molecule Ceacam5 nanobodyAnti-Carcinoembryonic Antigen nanobodyAnti-Cea nanobodyAnti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 nanobodyAnti-Cea Cell Adhesion Molecule 5 nanobodyAnti-Meconium Antigen 100 nanobodyAnti-Cd Antigen Cd66e nanobodyAnti-CEACAM5 nanobodyAnti-CEA nanobody |
Information sourced from Uniprot.org