Anti-CD66e/CEA/CEACAM5 antibody (Met1-Ala685) [1A088] (STJA0021926)

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STJA0021926
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: ELISA/IHC/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Cell Adhesion Molecule Ceacam5 (Met1-Ala685) is suitable for use in ELISA, Immunohistochemistry and Western Blot research applications.
Clonality : Monoclonal
Clone ID : 1A088
Conjugation: Unconjugated
Isotype: IgG1
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: CEACAM5
Gene ID: 1048
Uniprot ID: CEAM5_HUMAN
Immunogen Region: Met1-Ala685
Immunogen: Mammalian cells-derived recombinant Human CD66e/CEA/CEACAM5 (Met1-Ala685)
Post Translational Modifications Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
Function Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression.induces resistance to anoikis of colorectal carcinoma cells. (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer.
Protein Name Cell Adhesion Molecule Ceacam5
Carcinoembryonic Antigen
Cea
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5
Cea Cell Adhesion Molecule 5
Meconium Antigen 100
Cd Antigen Cd66e
Database Links Reactome: R-HSA-163125
Reactome: R-HSA-202733
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Apical Cell Membrane
Cell Surface
Localized To The Apical Glycocalyx Surface
Alternative Antibody Names Anti-Cell Adhesion Molecule Ceacam5 antibody
Anti-Carcinoembryonic Antigen antibody
Anti-Cea antibody
Anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 antibody
Anti-Cea Cell Adhesion Molecule 5 antibody
Anti-Meconium Antigen 100 antibody
Anti-Cd Antigen Cd66e antibody
Anti-CEACAM5 antibody
Anti-CEA antibody

Information sourced from Uniprot.org

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