Anti-CD64/FCGR1A nanobody [SAA2152] (STJN000615)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-High Affinity Immunoglobulin Gamma Fc Receptor I is suitable for use in Universaling and ELISA research applications. |
| Applications | Blocking/ELISA |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA2152 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | FCGR1A |
| Gene ID | 2209 |
| Uniprot ID | FCGR1_HUMAN |
Additional Info
| Post Translational Modifications | Phosphorylated on serine residues. |
| Function | High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells. |
| Protein Name | High Affinity Immunoglobulin Gamma Fc Receptor IIgg Fc Receptor IFc-Gamma RiFcriFc-Gamma RiaFcgammariaCd Antigen Cd64 |
| Database Links | Reactome: R-HSA-1236978Reactome: R-HSA-198933Reactome: R-HSA-2029481Reactome: R-HSA-2029482Reactome: R-HSA-2029485Reactome: R-HSA-877300Reactome: R-HSA-9664323 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinStabilized At The Cell Membrane Through Interaction With Fcer1g |
| Alternative Nanobody Names | Anti-High Affinity Immunoglobulin Gamma Fc Receptor I nanobodyAnti-Igg Fc Receptor I nanobodyAnti-Fc-Gamma Ri nanobodyAnti-Fcri nanobodyAnti-Fc-Gamma Ria nanobodyAnti-Fcgammaria nanobodyAnti-Cd Antigen Cd64 nanobodyAnti-FCGR1A nanobodyAnti-FCG1 nanobodyAnti-FCGR1 nanobodyAnti-IGFR1 nanobody |
Information sourced from Uniprot.org