Anti-CD64/FCGR1A nanobody [SAA2152] (STJN000615)

SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
STJN000615
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General Information

Short DescriptionAlpaca monoclonal nanobody anti-High Affinity Immunoglobulin Gamma Fc Receptor I is suitable for use in Universaling and ELISA research applications.
ApplicationsBlocking/ELISA
HostAlpaca
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDSAA2152
IsotypeVHH-8His-Cys-tag
ConjugationUnconjugated
Concentration1 mg/mL
PurificationPurified by Nickel column.
Formulation0.01M PBS, pH 7.4.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.

Target Information

Gene SymbolFCGR1A
Gene ID2209
Uniprot IDFCGR1_HUMAN

Additional Info

Post Translational Modifications Phosphorylated on serine residues.
Function High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells.
Protein Name High Affinity Immunoglobulin Gamma Fc Receptor I
Igg Fc Receptor I
Fc-Gamma Ri
Fcri
Fc-Gamma Ria
Fcgammaria
Cd Antigen Cd64
Database Links Reactome: R-HSA-1236978
Reactome: R-HSA-198933
Reactome: R-HSA-2029481
Reactome: R-HSA-2029482
Reactome: R-HSA-2029485
Reactome: R-HSA-877300
Reactome: R-HSA-9664323
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Stabilized At The Cell Membrane Through Interaction With Fcer1g
Alternative Nanobody Names Anti-High Affinity Immunoglobulin Gamma Fc Receptor I nanobody
Anti-Igg Fc Receptor I nanobody
Anti-Fc-Gamma Ri nanobody
Anti-Fcri nanobody
Anti-Fc-Gamma Ria nanobody
Anti-Fcgammaria nanobody
Anti-Cd Antigen Cd64 nanobody
Anti-FCGR1A nanobody
Anti-FCG1 nanobody
Anti-FCGR1 nanobody
Anti-IGFR1 nanobody

Information sourced from Uniprot.org

Citations

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