| Host: |
Alpaca |
| Applications: |
Blocking/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : |
Alpaca monoclonal nanobody anti-High Affinity Immunoglobulin Gamma Fc Receptor I is suitable for use in Universaling and ELISA research applications. |
| Clonality : |
Monoclonal |
| Clone ID : |
SAA2152 |
| Conjugation: |
Unconjugated |
| Isotype: |
VHH-8His-Cys-tag |
| Formulation: |
0.01M PBS, pH 7.4. |
| Purification: |
Purified by Nickel column. |
| Concentration: |
1 mg/mL |
| Storage Instruction: |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
| Post Translational Modifications | Phosphorylated on serine residues. |
| Function | High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells. |
| Protein Name | High Affinity Immunoglobulin Gamma Fc Receptor IIgg Fc Receptor IFc-Gamma RiFcriFc-Gamma RiaFcgammariaCd Antigen Cd64 |
| Database Links | Reactome: R-HSA-1236978Reactome: R-HSA-198933Reactome: R-HSA-2029481Reactome: R-HSA-2029482Reactome: R-HSA-2029485Reactome: R-HSA-877300Reactome: R-HSA-9664323 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinStabilized At The Cell Membrane Through Interaction With Fcer1g |
| Alternative Nanobody Names | Anti-High Affinity Immunoglobulin Gamma Fc Receptor I nanobodyAnti-Igg Fc Receptor I nanobodyAnti-Fc-Gamma Ri nanobodyAnti-Fcri nanobodyAnti-Fc-Gamma Ria nanobodyAnti-Fcgammaria nanobodyAnti-Cd Antigen Cd64 nanobodyAnti-FCGR1A nanobodyAnti-FCG1 nanobodyAnti-FCGR1 nanobodyAnti-IGFR1 nanobody |
Information sourced from Uniprot.org
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