Host: |
Alpaca |
Applications: |
Blocking/ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : |
Alpaca monoclonal nanobody anti-High Affinity Immunoglobulin Gamma Fc Receptor I is suitable for use in Universaling and ELISA research applications. |
Clonality : |
Monoclonal |
Clone ID : |
SAA2152 |
Conjugation: |
Unconjugated |
Isotype: |
VHH-8His-Cys-tag |
Formulation: |
0.01M PBS, pH 7.4. |
Purification: |
Purified by Nickel column. |
Concentration: |
1 mg/mL |
Storage Instruction: |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Post Translational Modifications | Phosphorylated on serine residues. |
Function | High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells. |
Protein Name | High Affinity Immunoglobulin Gamma Fc Receptor IIgg Fc Receptor IFc-Gamma RiFcriFc-Gamma RiaFcgammariaCd Antigen Cd64 |
Database Links | Reactome: R-HSA-1236978Reactome: R-HSA-198933Reactome: R-HSA-2029481Reactome: R-HSA-2029482Reactome: R-HSA-2029485Reactome: R-HSA-877300Reactome: R-HSA-9664323 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinStabilized At The Cell Membrane Through Interaction With Fcer1g |
Alternative Nanobody Names | Anti-High Affinity Immunoglobulin Gamma Fc Receptor I nanobodyAnti-Igg Fc Receptor I nanobodyAnti-Fc-Gamma Ri nanobodyAnti-Fcri nanobodyAnti-Fc-Gamma Ria nanobodyAnti-Fcgammaria nanobodyAnti-Cd Antigen Cd64 nanobodyAnti-FCGR1A nanobodyAnti-FCG1 nanobodyAnti-FCGR1 nanobodyAnti-IGFR1 nanobody |
Information sourced from Uniprot.org