| Host: |
Human |
| Applications: |
FC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : |
Human monoclonal antibody anti-High Affinity Immunoglobulin Gamma Fc Receptor I is suitable for use in Flow Cytometry research applications. |
| Clonality : |
Monoclonal |
| Clone ID : |
MDX-33 |
| Conjugation: |
PE |
| Isotype: |
IgG1k |
| Formulation: |
0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. |
| Purification: |
Purified |
| Concentration: |
0.5 mg/mL |
| Storage Instruction: |
Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Post Translational Modifications | Phosphorylated on serine residues. |
| Function | High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells. |
| Protein Name | High Affinity Immunoglobulin Gamma Fc Receptor IIgg Fc Receptor IFc-Gamma RiFcriFc-Gamma RiaFcgammariaCd Antigen Cd64 |
| Database Links | Reactome: R-HSA-1236978Reactome: R-HSA-198933Reactome: R-HSA-2029481Reactome: R-HSA-2029482Reactome: R-HSA-2029485Reactome: R-HSA-877300Reactome: R-HSA-9664323 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinStabilized At The Cell Membrane Through Interaction With Fcer1g |
| Alternative Antibody Names | Anti-High Affinity Immunoglobulin Gamma Fc Receptor I antibodyAnti-Igg Fc Receptor I antibodyAnti-Fc-Gamma Ri antibodyAnti-Fcri antibodyAnti-Fc-Gamma Ria antibodyAnti-Fcgammaria antibodyAnti-Cd Antigen Cd64 antibodyAnti-FCGR1A antibodyAnti-FCG1 antibodyAnti-FCGR1 antibodyAnti-IGFR1 antibody |
Information sourced from Uniprot.org
