| Host: |
Rabbit |
| Applications: |
WB/FC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : |
Rabbit monoclonal anti-CD64 for use in WB and FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : |
Monoclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| Purification: |
Affinity Purified |
| Dilution Range: |
WB-1:1000-1:5000FC-1:100-1:500 |
| Storage Instruction: |
Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Tissue Specificity | Monocyte/macrophage specific. |
| Post Translational Modifications | Phosphorylated on serine residues. |
| Function | High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells. |
| Protein Name | High Affinity Immunoglobulin Gamma Fc Receptor IIgg Fc Receptor IFc-Gamma RiFcriFc-Gamma RiaFcgammariaCd Antigen Cd64 |
| Database Links | Reactome: R-HSA-1236978Reactome: R-HSA-198933Reactome: R-HSA-2029481Reactome: R-HSA-2029482Reactome: R-HSA-2029485Reactome: R-HSA-877300Reactome: R-HSA-9664323 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinStabilized At The Cell Membrane Through Interaction With Fcer1g |
| Alternative Antibody Names | Anti-High Affinity Immunoglobulin Gamma Fc Receptor I antibodyAnti-Igg Fc Receptor I antibodyAnti-Fc-Gamma Ri antibodyAnti-Fcri antibodyAnti-Fc-Gamma Ria antibodyAnti-Fcgammaria antibodyAnti-Cd Antigen Cd64 antibodyAnti-FCGR1A antibodyAnti-FCG1 antibodyAnti-FCGR1 antibodyAnti-IGFR1 antibody |
Information sourced from Uniprot.org
