| Short Description : | Rabbit monoclonal CD62E/E-Selectin (22-230 aa) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | SRM5407 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:1000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SELE |
| Gene ID: | 6401 |
| Uniprot ID: | LYAM2_HUMAN |
| Immunogen Region: | 22-230 aa |
| Immunogen Sequence: | WSYNTSTEAMTYDEASAYCQ QRYTHLVAIQNKEEIEYLNS ILSYSPSYYWIGIRKVNNVW VWVGTQKPLTEEAKNWAPGE PNNRQKDEDCVEIYIKREKD VGMWNDERCSKKKLALCYTA ACTNTSCSGHGECVETINNY TCKCDPGFSGLKCEQIVNCT ALESPEHGSLVCSHPLGNFS YNSSCSISCDRGYLPSSMET MQCMSSGEW |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-230 of human CD62E/E-Selectin (NP_000441.2). |
| Function | Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis. |
| Protein Name | E-SelectinCd62 Antigen-Like Family Member EEndothelial Leukocyte Adhesion Molecule 1Elam-1Leukocyte-Endothelial Cell Adhesion Molecule 2Lecam2Cd Antigen Cd62e |
| Database Links | Reactome: R-HSA-202733 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-E-Selectin antibodyAnti-Cd62 Antigen-Like Family Member E antibodyAnti-Endothelial Leukocyte Adhesion Molecule 1 antibodyAnti-Elam-1 antibodyAnti-Leukocyte-Endothelial Cell Adhesion Molecule 2 antibodyAnti-Lecam2 antibodyAnti-Cd Antigen Cd62e antibodyAnti-SELE antibodyAnti-ELAM1 antibody |
Information sourced from Uniprot.org
