Anti-CD61 antibody [IHC061] (STJA0042071)

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STJA0042071
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Host: Mouse
Applications: IHC-p
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal anti-CD61 for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : IHC061
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Dilution Range: 1:50-1:200
Storage Instruction: Store at 2-8°C for up to 1 year. Do not freeze.
Specificity: Tested and validated on bone marrow tissue.
Background Cluster of Differentiation 61 (CD61) , also known as Glycoprotein IIIa or GPIIIa, is an antigen expressed on megakaryocytes, platelets, myeloid cells, monocytes, endothelial cells, smooth muscle cells, and macrophages. It is involved in platelet aggregation and acts as a receptor for fibrinogen, fibronectin, von Willebrand factor, and vitronectin. Anti-CD61 is used for identifying megakaryocytopoiesis, as seen in megakaryoblastic leukemias, myelodysplastic disorders, and acute myeloid leukemias. CD61 is also indicated as a marker for platelet adhesion in advanced atherosclerosis and has been reported in the identification of fat embolism in pulmonary tissue.

Information sourced from Uniprot.org

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