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Anti-CD59 antibody (51-100 aa) (STJ96617)

Western blot analysis of lysate from K562 cells, using CD59 Antibody.
Immunohistochemical analysis of paraffin-embedded Human Bladder. 1, Antibody was diluted at 1:200 (4°C overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).
Immunohistochemical analysis of paraffin-embedded Human Bladder. 1, Antibody was diluted at 1:200 (4°C overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).
Immunohistochemical analysis of paraffin-embedded Human Bladder. 1, Antibody was diluted at 1:200 (4°C overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).
Immunohistochemical analysis of paraffin-embedded human-colon, antibody was diluted at 1:100
Immunohistochemical analysis of paraffin-embedded human-heart, antibody was diluted at 1:100
Immunohistochemical analysis of paraffin-embedded human-heart, antibody was diluted at 1:100
Western blot analysis of K562 cells using CD59 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-CD59 antibody (51-100 aa) (STJ96617)

SKU:

STJ96617

£46.00 - £226.00

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CD59 glycoprotein (51-100 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC-P 1:100-300 ELISA 1:20000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CD59
Gene ID:	966
Uniprot ID:	CD59_HUMAN
Immunogen Region:	51-100 aa
Specificity:	CD59 Polyclonal Antibody detects endogenous levels of CD59 protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the Internal region of human CD59 at the amino acid range 51-100

Function	Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.
Protein Name	Cd59 Glycoprotein 1f5 Antigen 20 Kda Homologous Restriction Factor Hrf-20 Hrf20 Mac-Inhibitory Protein Mac-Ip Mem43 Antigen Membrane Attack Complex Inhibition Factor Macif Membrane Inhibitor Of Reactive Lysis Mirl Protectin Cd Antigen Cd59
Database Links	Reactome: R-HSA-204005 Reactome: R-HSA-5694530 Reactome: R-HSA-6798695 Reactome: R-HSA-6807878 Reactome: R-HSA-977606
Cellular Localisation	Cell Membrane Lipid-Anchor Gpi-Anchor Secreted Soluble Form Found In A Number Of Tissues
Alternative Antibody Names	Anti-Cd59 Glycoprotein antibody Anti-1f5 Antigen antibody Anti-20 Kda Homologous Restriction Factor antibody Anti-Hrf-20 antibody Anti-Hrf20 antibody Anti-Mac-Inhibitory Protein antibody Anti-Mac-Ip antibody Anti-Mem43 Antigen antibody Anti-Membrane Attack Complex Inhibition Factor antibody Anti-Macif antibody Anti-Membrane Inhibitor Of Reactive Lysis antibody Anti-Mirl antibody Anti-Protectin antibody Anti-Cd Antigen Cd59 antibody Anti-CD59 antibody Anti-MIC11 antibody Anti-MIN1 antibody Anti-MIN2 antibody Anti-MIN3 antibody Anti-MSK21 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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