• Western blot analysis of extracts of various cell lines, using CD58 Antibody (STJ27651) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-CD58 antibody (40-220) (STJ27651)

SKU:
STJ27651

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CD58 (40-220) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CD58
Gene ID: 965
Uniprot ID: LFA3_HUMAN
Immunogen Region: 40-220
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-220 of human CD58 (NP_001770.1).
Immunogen Sequence: NVTFHVPSNVPLKEVLWKKQ KDKVAELENSEFRAFSSFKN RVYLDTVSGSLTIYNLTSSD EDEYEMESPNITDTMKFFLY VLESLPSPTLTCALTNGSIE VQCMIPEHYNSHRGLIMYSW DCPMEQCKRNSTSIYFKMEN DLPQKIQCTLSNPLFNTTSS IILTTCIPSSGHSRHRYALI P
Function Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
Protein Name Lymphocyte Function-Associated Antigen 3
Ag3
Surface Glycoprotein Lfa-3
Cd Antigen Cd58
Database Links Reactome: R-HSA-202733
Reactome: R-HSA-6798695
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Lymphocyte Function-Associated Antigen 3 antibody
Anti-Ag3 antibody
Anti-Surface Glycoprotein Lfa-3 antibody
Anti-Cd Antigen Cd58 antibody
Anti-CD58 antibody
Anti-LFA3 antibody

Information sourced from Uniprot.org

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