Anti-CD57 antibody IHC Human tonsil STJ180066

Anti-CD57 antibody [NK‐1] (STJ180066)

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STJ180066
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Short Description :Mouse monoclonal CD57 antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-P
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :NK‐1
Isotype:IgM
Conjugation:Unconjugated
Purification:Affinity purified
Dilution Range:1:100‐200
Formulation:Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Storage Instruction:Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.
Gene Symbol:B3GAT1
Gene ID:27087
Uniprot ID:B3GA1_HUMAN
Immunogen:Human peripheral blood mononuclear cells
Specificity:Positive control: Lymph node or tonsil
Tissue Specificity Mainly expressed in the brain.
Post Translational Modifications The soluble form derives from the membrane form by proteolytic processing.
Function Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group.
Protein Name Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1
Beta-1 -3-Glucuronyltransferase 1
Glucuronosyltransferase P
Glcat-P
Udp-Glcua -Glycoprotein Beta-1 -3-Glucuronyltransferase
Glcuat-P
Database Links Reactome: R-HSA-1971475
Cellular Localisation Isoform 1: Golgi Apparatus Membrane
Single-Pass Type Ii Membrane Protein
Secreted
Isoform 2: Golgi Apparatus Membrane
Endoplasmic Reticulum Membrane
Alternative Antibody Names Anti-Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 antibody
Anti-Beta-1 -3-Glucuronyltransferase 1 antibody
Anti-Glucuronosyltransferase P antibody
Anti-Glcat-P antibody
Anti-Udp-Glcua -Glycoprotein Beta-1 -3-Glucuronyltransferase antibody
Anti-Glcuat-P antibody
Anti-B3GAT1 antibody
Anti-GLCATP antibody

Information sourced from Uniprot.org

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