Anti-CD57 antibody [NK-1] (STJ16100013)

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STJ16100013
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Short Description :Mouse monoclonal anti-CD57 for use in FC, IF and IHC in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:FC/IF/IHC
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :NK-1
Isotype:IgMk
Conjugation:Unconjugated
Concentration:Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL.
Purification:Affinity purified from tissue culture.
Dilution Range:Flow cytometry (0, 5-1, 0 µg/million cells in 0, 1 ml). Immunofluorescence (0, 5-1, 0 µg/ml). Immunohistology (1-2 µg/ml for 30-60 min at RT; staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for
Formulation:PBS with 0.02% Sodium Azide.
Storage Instruction:Store for up to 1 year at 2-8°C upon receipt.
Immunogen:A BALB/c mouse was immunized with human PBL. Fusion partner: NS-1.
Background NK-1 reacts with CD57, a 110 kDa antigen present on the surface of human NK-cells and Tcell subsets. In adult peripheral blood 20% of mononuclear cells are positive. Other positive tissues include peripheral nerves (myelin-associated glycoprotein) and prostate. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastomas. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.

Information sourced from Uniprot.org