Host: | Mouse |
Applications: | FC/IF/IHC |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-CD57 is suitable for use in Flow Cytometry, Immunofluorescence and Immunohistochemistry research applications. |
Clonality : | Monoclonal |
Clone ID : | NK-1 |
Conjugation: | Unconjugated |
Isotype: | IgMk |
Formulation: | PBS with 0.02% Sodium Azide. |
Purification: | Affinity purified from tissue culture. |
Concentration: | Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
Dilution Range: | Flow cytometry (0, 5-1, 0 µg/million cells in 0, 1 ml). Immunofluorescence (0, 5-1, 0 µg/ml). Immunohistology (1-2 µg/ml for 30-60 min at RT; staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for |
Storage Instruction: | Store for up to 1 year at 2-8°C upon receipt. |
Immunogen: | A BALB/c mouse was immunized with human PBL. Fusion partner: NS-1. |
Background | NK-1 reacts with CD57, a 110 kDa antigen present on the surface of human NK-cells and Tcell subsets. In adult peripheral blood 20% of mononuclear cells are positive. Other positive tissues include peripheral nerves (myelin-associated glycoprotein) and prostate. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastomas. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA. |
Information sourced from Uniprot.org