| Host: | Mouse |
| Applications: | FC |
| Reactivity: | Human |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Neural Cell Adhesion Molecule 1 is suitable for use in Flow Cytometry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | HI55a |
| Conjugation: | PerCP/Cyanine 5.5 |
| Isotype: | IgG2ak |
| Formulation: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Purification: | Affinity purified |
| Concentration: | 5 Mu L/Tests |
| Storage Instruction: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Gene Symbol: | NCAM1 |
| Gene ID: | 4684 |
| Uniprot ID: | NCAM1_HUMAN |
| Post Translational Modifications | Polysialylated at Asn-459 and Asn-488 by ST8SIA2 and ST8SIA4. Polysialylation modulates cell interactions by confering both attractive and repulsive properties that are highly regulated by ST8SIA2 and ST8SIA4. Polysialylation is formed on a-2,3-linked sialic acid of core glycans. |
| Function | This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. (Microbial infection) Acts as a receptor for rabies virus. (Microbial infection) Acts as a receptor for Zika virus. |
| Protein Name | Neural Cell Adhesion Molecule 1 N-Cam-1 Ncam-1 Cd Antigen Cd56 |
| Database Links | Reactome: R-HSA-3000178 Reactome: R-HSA-375165 Reactome: R-HSA-419037 Reactome: R-HSA-445144 Reactome: R-HSA-5673001 Reactome: R-HSA-877300 |
| Cellular Localisation | Isoform 1: Cell Membrane Single-Pass Type I Membrane Protein Isoform 2: Cell Membrane Isoform 3: Cell Membrane Lipid-Anchor Gpi-Anchor Isoform 4: Cell Membrane Isoform 5: Secreted Isoform 6: Secreted |
| Alternative Antibody Names | Anti-Neural Cell Adhesion Molecule 1 antibody Anti-N-Cam-1 antibody Anti-Ncam-1 antibody Anti-Cd Antigen Cd56 antibody Anti-NCAM1 antibody Anti-NCAM antibody |
Information sourced from Uniprot.org