![Mouse bone marrow cells were stained with Anti-CD49b antibody (STJA0000701) [Used at 0.2 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained bone marrow cells (blank black histogram) were used as control.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/145554/292212/STJA0000701_1__68523.1631206055.jpg?c=1 "Mouse bone marrow cells were stained with Anti-CD49b antibody (STJA0000701) [Used at 0.2 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained bone marrow cells (blank black histogram) were used as control.")
![Mouse bone marrow cells were stained with Anti-CD49b antibody (STJA0000701) [Used at 0.2 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained bone marrow cells (blank black histogram) were used as control.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/145554/292212/STJA0000701_1__68523.1631206055.jpg?c=1 "Mouse bone marrow cells were stained with Anti-CD49b antibody (STJA0000701) [Used at 0.2 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained bone marrow cells (blank black histogram) were used as control.")
| Host: | Rat |
| Applications: | FC |
| Reactivity: | Mouse |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | Rat monoclonal antibody anti-Integrin alpha-2 is suitable for use in Flow Cytometry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | DX5 |
| Conjugation: | PE/Cyanine5 |
| Isotype: | IgMk |
| Formulation: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Concentration: | 0.2 mg/mL |
| Storage Instruction: | Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
| Gene Symbol: | Itga2 |
| Gene ID: | 16398 |
| Uniprot ID: | ITA2_MOUSE |
| Function | Integrin alpha-2/beta-1 is a collagen receptor, being responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. It is also a receptor for laminins, collagen C-propeptides and E-cadherin. Mice homozygous for a null mutation in the alpha-2 die very early in embryogenesis. |
| Protein Name | Integrin Alpha-2 Cd49 Antigen-Like Family Member B Collagen Receptor Platelet Membrane Glycoprotein Ia Gpia Vla-2 Subunit Alpha Cd Antigen Cd49b |
| Database Links | Reactome: R-MMU-216083 Reactome: -MMU-3000170 Reactome: -MMU-3000178 Reactome: -MMU-8874081 |
| Cellular Localisation | Membrane Single-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Integrin Alpha-2 antibody Anti-Cd49 Antigen-Like Family Member B antibody Anti-Collagen Receptor antibody Anti-Platelet Membrane Glycoprotein Ia antibody Anti-Gpia antibody Anti-Vla-2 Subunit Alpha antibody Anti-Cd Antigen Cd49b antibody Anti-Itga2 antibody |
Information sourced from Uniprot.org