| Host: | Rabbit |
| Applications: | FC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Conjugation: | APC |
| Isotype: | IgG |
| Formulation: | PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis) , pH 7.3. |
| Purification: | Affinity purification |
| Dilution Range: | FC, 5 Mu l per 10^6 cells in 100 Mu l volume |
| Storage Instruction: | Store at 4°C for up to 1 year from the date of receipt. Do not freeze. |
| Gene Symbol: | GP1BA |
| Gene ID: | 2811 |
| Uniprot ID: | GP1BA_HUMAN |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Post Translational Modifications | Glycocalicin is the product of a proteolytic cleavage/shedding, catalyzed by ADAM17, which releases most of the extracellular domain. Binding sites for vWF and thrombin are in this part of the protein. |
| Function | GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium. |
| Protein Name | Platelet Glycoprotein Ib Alpha ChainGp-Ib AlphaGpib-AlphaGpibaGlycoprotein IbalphaAntigen Cd42b-AlphaCd Antigen Cd42b Cleaved Into - Glycocalicin |
| Database Links | Reactome: R-HSA-140837Reactome: R-HSA-430116Reactome: R-HSA-75892Reactome: R-HSA-76009Reactome: R-HSA-8936459Reactome: R-HSA-9673221Reactome: R-HSA-9845620Reactome: R-HSA-9846298 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Platelet Glycoprotein Ib Alpha Chain antibodyAnti-Gp-Ib Alpha antibodyAnti-Gpib-Alpha antibodyAnti-Gpiba antibodyAnti-Glycoprotein Ibalpha antibodyAnti-Antigen Cd42b-Alpha antibodyAnti-Cd Antigen Cd42b Cleaved Into - Glycocalicin antibodyAnti-GP1BA antibody |
Information sourced from Uniprot.org