| Host: | Mouse |
| Applications: | FC/IHC-F |
| Reactivity: | Non-Human Primates/Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-CD41b is suitable for use in Flow Cytometry and Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | HIP2 |
| Conjugation: | Unconjugated |
| Isotype: | IgG3 |
| Formulation: | Tris buffered saline (TBS) solution with 15 mM sodium azide |
| Concentration: | 1 mg/mL |
| Storage Instruction: | Store at 2-8°C upon receipt. |
| Background | CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation. |
Information sourced from Uniprot.org