![Anti-CD40/TNFRSF5 nanobody [SAA1164] (STJN000180)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/200793/412975/STJN000180-SDS-PAGE-1__85370.1749232500.jpg?c=1 "Anti-CD40/TNFRSF5 nanobody [SAA1164] (STJN000180)")
![Anti-CD40/TNFRSF5 nanobody [SAA1164] (STJN000180)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/200793/412975/STJN000180-SDS-PAGE-1__85370.1749232500.jpg?c=1 "Anti-CD40/TNFRSF5 nanobody [SAA1164] (STJN000180)")
Anti-CD40/TNFRSF5 nanobody [SAA1164] (STJN000180)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-Tumor Necrosis Factor Receptor Superfamily Member 5 is suitable for use in ELISA and SPR research applications. |
| Applications | ELISA/SPR |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1164 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | CD40 |
| Gene ID | 958 |
| Uniprot ID | TNR5_HUMAN |
Additional Info
| Function | Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 5B-Cell Surface Antigen Cd40Bp50Cd40l ReceptorCdw40Cd Antigen Cd40 |
| Database Links | Reactome: R-HSA-198933 P25942-1Reactome: R-HSA-5668541 P25942-1Reactome: R-HSA-5676594 P25942-1 |
| Cellular Localisation | Isoform I: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform Ii: Secreted |
| Alternative Nanobody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 5 nanobodyAnti-B-Cell Surface Antigen Cd40 nanobodyAnti-Bp50 nanobodyAnti-Cd40l Receptor nanobodyAnti-Cdw40 nanobodyAnti-Cd Antigen Cd40 nanobodyAnti-CD40 nanobodyAnti-TNFRSF5 nanobody |
Information sourced from Uniprot.org