Anti-CD40/TNFRSF5 antibody [4D11] (STJA0027296)

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STJA0027296
€254.38 - €368.13
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Host: Human
Applications: Blocking/FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Human monoclonal antibody anti-Tumor Necrosis Factor Receptor Superfamily Member 5 is suitable for use in Universaling and Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : 4D11
Conjugation: Unconjugated
Isotype: IgG4k
Formulation: 0.01M PBS, pH 7.4.
Purification: Protein A/G purified from cell culture supernatant.
Concentration: 1 mg/ml
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: CD40
Gene ID: 958
Uniprot ID: TNR5_HUMAN
Function Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 5
B-Cell Surface Antigen Cd40
Bp50
Cd40l Receptor
Cdw40
Cd Antigen Cd40
Database Links Reactome: R-HSA-198933 P25942-1
Reactome: R-HSA-5668541 P25942-1
Reactome: R-HSA-5676594 P25942-1
Cellular Localisation Isoform I: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform Ii: Secreted
Alternative Antibody Names Anti-Tumor Necrosis Factor Receptor Superfamily Member 5 antibody
Anti-B-Cell Surface Antigen Cd40 antibody
Anti-Bp50 antibody
Anti-Cd40l Receptor antibody
Anti-Cdw40 antibody
Anti-Cd Antigen Cd40 antibody
Anti-CD40 antibody
Anti-TNFRSF5 antibody

Information sourced from Uniprot.org