Anti-CD40 antibody {ABflo® 488} (STJ11108444)

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STJ11108444
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Conjugation: ABflo® 488
Isotype: IgG
Formulation: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis) , pH 7.3.
Purification: Affinity purification
Dilution Range: FC, 5 Mu l per 10^6 cells in 100 Mu l volume
Storage Instruction: Store at 4°C for up to 1 year from the date of receipt. Do not freeze.
Gene Symbol: CD40
Gene ID: 958
Uniprot ID: TNR5_HUMAN
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tissue Specificity B-cells and in primary carcinomas.
Function Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 5
B-Cell Surface Antigen Cd40
Bp50
Cd40l Receptor
Cdw40
Cd Antigen Cd40
Database Links Reactome: R-HSA-198933 P25942-1
Reactome: R-HSA-5668541 P25942-1
Reactome: R-HSA-5676594 P25942-1
Cellular Localisation Isoform I: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform Ii: Secreted
Alternative Antibody Names Anti-Tumor Necrosis Factor Receptor Superfamily Member 5 antibody
Anti-B-Cell Surface Antigen Cd40 antibody
Anti-Bp50 antibody
Anti-Cd40l Receptor antibody
Anti-Cdw40 antibody
Anti-Cd Antigen Cd40 antibody
Anti-CD40 antibody
Anti-TNFRSF5 antibody

Information sourced from Uniprot.org

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