Anti-CD38/ADPRC 1 nanobody [SAA2057] (STJN000575)

SKU:
STJN000575
£378.50 - £1,632.50
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Host: Alpaca
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Alpaca monoclonal nanobody anti-Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA2057
Conjugation: Unconjugated
Isotype: VHH-8His-Cys-tag
Formulation: 0.01M PBS, pH 7.4.
Purification: Purified by Nickel column.
Concentration: 2.1 mg/mL
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol: CD38
Gene ID: 952
Uniprot ID: CD38_HUMAN
Function Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion. Synthesizes the Ca(2+) mobilizer nicotinate-adenine dinucleotide phosphate, NAADP(+), from 2'-phospho-cADPR and nicotinic acid, as well as from NADP(+) and nicotinic acid. At both pH 5.0 and pH 7.4 preferentially transforms 2'-phospho-cADPR into NAADP(+), while preferentially cleaving NADP(+) to cADPR and ADPRP rather than into NADDP(+). Has cADPR hydrolase activity.
Protein Name Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1
2'-Phospho-Adp-Ribosyl Cyclase
2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase
2'-Phospho-Cyclic-Adp-Ribose Transferase
Adp-Ribosyl Cyclase 1
Adprc 1
Cyclic Adp-Ribose Hydrolase 1
Cadpr Hydrolase 1
T10
Cd Antigen Cd38
Database Links Reactome: R-HSA-196807
Cellular Localisation Cell Surface
Membrane
Single-Pass Type Ii Membrane Protein
Alternative Nanobody Names Anti-Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 nanobody
Anti-2'-Phospho-Adp-Ribosyl Cyclase nanobody
Anti-2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase nanobody
Anti-2'-Phospho-Cyclic-Adp-Ribose Transferase nanobody
Anti-Adp-Ribosyl Cyclase 1 nanobody
Anti-Adprc 1 nanobody
Anti-Cyclic Adp-Ribose Hydrolase 1 nanobody
Anti-Cadpr Hydrolase 1 nanobody
Anti-T10 nanobody
Anti-Cd Antigen Cd38 nanobody
Anti-CD38 nanobody

Information sourced from Uniprot.org