![Anti-CD38/ADPRC 1 nanobody [SAA0895] (STJN000188)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/200801/412983/STJN000188-SDS-PAGE-1__92947.1749232507.jpg?c=1 "Anti-CD38/ADPRC 1 nanobody [SAA0895] (STJN000188)")
![Anti-CD38/ADPRC 1 nanobody [SAA0895] (STJN000188)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/200801/412983/STJN000188-SDS-PAGE-1__92947.1749232507.jpg?c=1 "Anti-CD38/ADPRC 1 nanobody [SAA0895] (STJN000188)")
Anti-CD38/ADPRC 1 nanobody [SAA0895] (STJN000188)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 is suitable for use in ELISA research applications. |
| Applications | ELISA |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0895 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | CD38 |
| Gene ID | 952 |
| Uniprot ID | CD38_HUMAN |
Additional Info
| Function | Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion. Synthesizes the Ca(2+) mobilizer nicotinate-adenine dinucleotide phosphate, NAADP(+), from 2'-phospho-cADPR and nicotinic acid, as well as from NADP(+) and nicotinic acid. At both pH 5.0 and pH 7.4 preferentially transforms 2'-phospho-cADPR into NAADP(+), while preferentially cleaving NADP(+) to cADPR and ADPRP rather than into NADDP(+). Has cADPR hydrolase activity. |
| Protein Name | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 12'-Phospho-Adp-Ribosyl Cyclase2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase2'-Phospho-Cyclic-Adp-Ribose TransferaseAdp-Ribosyl Cyclase 1Adprc 1Cyclic Adp-Ribose Hydrolase 1Cadpr Hydrolase 1T10Cd Antigen Cd38 |
| Database Links | Reactome: R-HSA-196807 |
| Cellular Localisation | Cell SurfaceMembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Nanobody Names | Anti-Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 nanobodyAnti-2'-Phospho-Adp-Ribosyl Cyclase nanobodyAnti-2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase nanobodyAnti-2'-Phospho-Cyclic-Adp-Ribose Transferase nanobodyAnti-Adp-Ribosyl Cyclase 1 nanobodyAnti-Adprc 1 nanobodyAnti-Cyclic Adp-Ribose Hydrolase 1 nanobodyAnti-Cadpr Hydrolase 1 nanobodyAnti-T10 nanobodyAnti-Cd Antigen Cd38 nanobodyAnti-CD38 nanobody |
Information sourced from Uniprot.org