| Function | Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion. |
| Protein Name | Complement Component Receptor 1-Like ProteinComplement Regulatory Protein CrryProtein P65 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Complement Component Receptor 1-Like Protein antibodyAnti-Complement Regulatory Protein Crry antibodyAnti-Protein P65 antibodyAnti-Cr1l antibodyAnti-Crry antibodyAnti-Cry antibody |
Information sourced from Uniprot.org
