Anti-CD35/CR1/CD21b antibody [7G6] {FITC} (STJA0028276)

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STJA0028276
£231.50 - £341.50
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Host: Rat
Applications: ELISA/FC
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Rat monoclonal antibody anti-Complement Component Receptor 1-Like Protein is suitable for use in ELISA and Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : 7G6
Conjugation: FITC
Isotype: IgG2bk
Formulation: 0.01M PBS, pH 7.4, 02% BSA, 0.05% Proclin 300
Purification: Purified
Concentration: 05 mg/mL
Storage Instruction: Store at 4°C for 12 months Protect from light Do not freeze
Gene Symbol: Cr1l
Gene ID: 12946
Uniprot ID: CR1L_MOUSE
Function Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion.
Protein Name Complement Component Receptor 1-Like Protein
Complement Regulatory Protein Crry
Protein P65
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Complement Component Receptor 1-Like Protein antibody
Anti-Complement Regulatory Protein Crry antibody
Anti-Protein P65 antibody
Anti-Cr1l antibody
Anti-Crry antibody
Anti-Cry antibody

Information sourced from Uniprot.org