Anti-CD339/JAG1 nanobody [SAA1285] (STJN000251)

SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
STJN000251
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General Information

Short DescriptionAlpaca monoclonal nanobody anti-Protein Jagged-1 is suitable for use in ELISA research applications.
ApplicationsELISA
HostAlpaca
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDSAA1285
IsotypeVHH-8His-Cys-tag
ConjugationUnconjugated
Concentration1 mg/mL
PurificationPurified by Nickel column.
Formulation0.01M PBS, pH 7.4.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.

Target Information

Gene SymbolJAG1
Gene ID182
Uniprot IDJAG1_HUMAN

Additional Info

Function Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro).
Protein Name Protein Jagged-1
Jagged1
Hj1
Cd Antigen Cd339
Database Links Reactome: R-HSA-2122948
Reactome: R-HSA-2644606
Reactome: R-HSA-2660826
Reactome: R-HSA-2691232
Reactome: R-HSA-2894862
Reactome: R-HSA-2979096
Reactome: R-HSA-8941856
Reactome: R-HSA-9013149
Reactome: R-HSA-9013423
Reactome: R-HSA-9013507
Reactome: R-HSA-9013700
Reactome: R-HSA-9831926
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Cell Membrane
Alternative Nanobody Names Anti-Protein Jagged-1 nanobody
Anti-Jagged1 nanobody
Anti-Hj1 nanobody
Anti-Cd Antigen Cd339 nanobody
Anti-JAG1 nanobody
Anti-JAGL1 nanobody

Information sourced from Uniprot.org

Citations

Product Review