| Host: | Mouse |
| Applications: | FC |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Protein Jagged-1 is suitable for use in Flow Cytometry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | B70 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1k |
| Formulation: | 0.01M PBS, pH 7.4. |
| Purification: | Protein A/G purified from cell culture supernatant. |
| Concentration: | 1 mg/ml |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | JAG1 |
| Gene ID: | 182 |
| Uniprot ID: | JAG1_HUMAN |
| Function | Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). |
| Protein Name | Protein Jagged-1Jagged1Hj1Cd Antigen Cd339 |
| Database Links | Reactome: R-HSA-2122948Reactome: R-HSA-2644606Reactome: R-HSA-2660826Reactome: R-HSA-2691232Reactome: R-HSA-2894862Reactome: R-HSA-2979096Reactome: R-HSA-8941856Reactome: R-HSA-9013149Reactome: R-HSA-9013423Reactome: R-HSA-9013507Reactome: R-HSA-9013700Reactome: R-HSA-9831926 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Protein Jagged-1 antibodyAnti-Jagged1 antibodyAnti-Hj1 antibodyAnti-Cd Antigen Cd339 antibodyAnti-JAG1 antibodyAnti-JAGL1 antibody |
Information sourced from Uniprot.org